Product Code : 130
Brand Name : Step-D Tablet
DICLOFENAC POTASSIUM 50MG +SERRATIOPEPTIDASE 10MG TABLET
Diclofenac Potassium is a non-steroidal anti-inflammatory agent (NSAIDs) with antipyretic and analgesic actions.
Serratiopeptidase is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15 used in the prevention of pain and swelling.
Indications and Usage:
? For the treatment of primary dysmenorrhea.
? For the treatment of mild to moderate pain.
? For the relief from the signs and symptoms of osteoarthritis.
? For the relief from the signs and symptoms of rheumatoid arthritis.
? Chronic inflammation.
? Headaches, muscle and joint pain.
? Serious diseases like cancer and heart disease.
? Superficial thrombophlebitis.
? Postoperative & traumatic swelling.
? Acute or chronic ear, nose or throat disorder.
Rationale of Combination:
Diclofenac Potassium is used as an anti-inflammatory agent to pacify mild to moderate pain and inflammation. Common conditions associated with pain and
inflammation include arthritis, trauma, surgery and fibermyalgia. Additionally, serratiopeptidase helps to reduce fluid retention in affected areas, which
contributes to proper drainage and a quicker recovery.
Diclofenac Potassium is an acetic acid non-steroidal anti-inflammatory drug (NSAIDs) with analgesic and antipyretic properties. Diclofenac Potassium inhibits the
production of prostaglandins by inhibiting pathways thereby exhibiting anti- inflammatory effects.
Absorption: Well absorbed following oral administration.
Distribution: widely distributed in animals. Plasma protein binding exhibited is >99%.
Elimination: hepatic metabolism leads to elimination through urine.
Serratiopeptidase is an enzyme isolated from a non-pathogenic bacteria called enterobacteria Serratia E15. Serratiopeptidase has powerful anti-inflammatory
properties and is particularly useful for post-traumatic swelling, fibrocystic breast disease and bronchitis. It is able to digest dead tissue, blood clots, cysts, and
Absorption: On oral administration, serratiopeptidase is absorbed in GI tract.
Distribution: Distributed throughout the body tissues, unchanged via systemic circulation. It reaches in higher concentration in inflamed tissues.
Serratiopeptidase levels in inflammatory exudates rises gradually with decline in blood levels indicating that serratiopeptidase is quite rapidly transferred to the
site of inflammation.
? Skin rash
? Gastrointestinal disturbance
Diclofenac sodium + Serratiopeptidase is contraindicated in patients with active GI bleeding or perforations, asthma, renal or hepatic disorders, hypertension,
porphyria, peri-operative pain in CABG surgery patients and bleeding disorders.
Diclofenac potassium+ Serratiopeptidase should not be taken concomitantly with other NSAIDs, anticoagulants including low-dose/LMW heparin, sucralfate,
triamterene, cyclosporine, cholestyramine, colestipol, digoxin, methotrexate and lithium.
Diclofenac potassium + Serratiopeptidase should be taken with food. Take the drug immediately after meals to avoid GI disturbances.
Store at 15-30°C.
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- Main Export Market(s)
- Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
- Main Domestic Market
- All India