Mode of administration
Alpha-Beta Arteether: Injectable.
Mechanism of action
Alpha-Beta Arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. ?-? Arteether is concentrated in parasitized erytrocytes. The functional group responsible for antimalarial activity of Alpha-Beta Arteether is endoperoxide bridge which inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.
Severe malaria including cerebral malaria & as a second line drug in chloroquine resistant malaria cases only.
Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives.