Indications and Usage:

• The drug is used to treat neuropathic pain caused by spinal cord injuries.
• Diabetes peripheral neuropathy.
• Fibromyalgia treatment
• Pain management, perioperative pain, and migraine treatment
• Provides support to the nervous system
• Memory and learning are improved
• Enhances energy
• Homocysteine levels are controlled
• Enhances cardiovascular health
• Boosts immune system function
• Supports brain and nerve function

Drug Interactions:

Inform the physician of any medical problems or allergies the patient has now or has ever had before taking this medicine.
The majority of drug interactions occur when the drug is combined with another or with a food. It is important that you tell a health expert about any other medications you are taking, including non-prescription medications, before you take this medication.

Mechanism of action:

Pregabalin combined with Methylcobalamin does not only inhibit neurotransmitter release but also promotes the regeneration of myelin.
The analgesic activity of pregabalin also reduces the pain associated with neuropathy. Combining Pregabalin and Methylcobalamin is useful in halting the progression of diabetic neuropathy and relieving its associated pain. The enzyme methionine synthase uses methylcobalamin to generate methionine by transferring methyl groups from homocysteine. Coronary artery disease is associated with elevated homocysteine levels. The conversion of methionine to S-adenoxylmethionine (SAM) can assist with a number of metabolic reactions, including the treatment of depression.